Summary: This book delves into how various brain diseases and conditions, such as epilepsy, syphilis, schizophrenia, and tumors, have impacted famous and infamous historical figures, thereby altering the course of history. It features individuals like Leonardo da Vinci, Vincent van Gogh, Adolf Hitler, Jack the Ripper, Arthur Inman (the world's longest diarist), Vaslav Nijinsky, Woody Guthrie, and Jack Ruby, examining conditions like temporal lobe epilepsy and hypergraphia.